Cold & Flu Treatment Over the Counter Aleve-D Sinus and Cold: What to Know By Kristina Herndon, RN Updated on August 04, 2023 Medically reviewed by Keri Peterson, MD Print Aleve-D Sinus and Cold is a cold medication that helps relieve sinus pain, nasal and sinus congestion, minor body aches, and headache. It contains a decongestant along with a fever-reducer/pain reliever. The effects last up to 12 hours. Aleve-D Sinus and Cold is kept behind the pharmacy counter because it contains pseudoephedrine. It is available without a prescription. This article discusses Aleve-D Sinus and Cold, what it's used for, and what its potential side effects are. Cecile Lavabre / Photographer's Choice / Getty Images Active Ingredients in Aleve-D Each caplet contains: Naproxen sodium 220mg (pain reliever/fever reducer) Pseudoephedrine HCl 120mg, extended release (nasal decongestant) Dosage and Directions Adults and children over 12 years old: 1 caplet every 12 hours, not to exceed 2 caplets in 24 hours Children under 12 years should not take this product unless directed to do so by a healthcare provider. Directions:Swallow whole, do not crush or chew.Drink a full glass of water with each dose. What Aleve-D is Used For Aleve-D Sinus and Cold helps relieve cold and flu symptoms including sinus pain and pressure, minor body aches and pains, headache, nasal and sinus congestion, and fever. Side Effects of Aleve-D Naproxen sodium may cause severe allergic reactions, which may include: Hives Facial swelling Wheezing or trouble breathing Shock Other adverse effects caused by naproxen can include: Abdominal pain Constipation Nausea Diarrhea GI bleeding Perforation Ulcers Headache Dizziness Pseudoephedrine can cause: Confusion or nervous feeling Headaches Nausea or vomiting Loss of appetite Atrial fibrillation or premature ventricular beats (abnormal heart rhythms) High blood pressure Shaking Restlessness Insomnia Warnings Do not use if you have ever had an allergic reaction to any other pain reliever/fever reducer. Do not use if you are now taking a medication known as an MAOI or for two weeks after stopping an MAOI. If you are not sure, contact your healthcare provider or pharmacist before taking this medication. May cause stomach bleeding. Keep out of reach of children. In case of overdose, contact Poison Control at (800) 222-1222 or go to an Emergency Room immediately. Ask a Healthcare Provider Before Use If... You consume more than 3 alcoholic beverages a day, which may increase the risk of stomach bleeding. You have heart disease. You have high blood pressure. You have thyroid disease. You have diabetes. You have trouble urinating due to an enlarged prostate gland. You have had serious side effects from any pain reliever or fever reducer. You are pregnant or breastfeeding. (Aleve-D may cause problems in an unborn child if taken during the third trimester of pregnancy.) Stop Use and Ask a Healthcare Provider If... You get nervous, dizzy or sleepless.You have nasal congestion that lasts more than 7 days.Your symptoms continue or get worse.You have trouble swallowing or you feel like the caplet is stuck in your throat.New or unexpected symptoms occur.You have stomach pain that begins while taking this product or mild stomach problems that do not go away.You have a fever that lasts longer than 3 days. If an allergic reaction occurs, seek medical attention immediately. Summary Aleve-D Cold and Sinus is available behind the counter without a prescription. It can help relieve nasal and sinus congestion, sinus pain, and other symptoms like headache and fever. Aleve-D should not be used in children under the age of 12. Don't take more than 1 caplet every 12 hours. Watch for side effects such as stomach pain or symptoms of an allergic reaction such as hives, wheezing, or facial swelling. Contact a healthcare provider before taking Aleve-D Cold and Sinus if you are pregnant or have a chronic health condition such as high blood pressure or diabetes. 2 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. U.S. Food and Drug Administration. NAPROSYN (naproxen) Suspension. National Library of Medicine. Pseudoephedrine. By Kristina Herndon, RN Kristina Herndon, BSN, RN, CPN, has been working in healthcare since 2002. She specializes in pediatrics and disease and infection prevention. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit